Axyntis — Company Profile

Axyntis Group Bioparc 8, rue de la Croix Jarry 75013 Paris France Tel.: +33 (0)1 44 06 77 00 Fax: +33 (0)1 44 06 76 99 Email: contact@axyntis.com Website: http://www.axyntis.com/

Leading fine and specialty chemicals company, French-based, Axyntis independent group with its 350 employees offers a deep rooted technical experience — the history of dyes activity started in 1881 at Saint-Marcel and the history of fine chemicals in 1879 at Grasse under the name "Schmoller et Bompard" for perfumery. This group designs innovative chemical processes and offers project management in close relationship with its customers.

Axyntis group has two divisions. One is dedicated to dyes: Steiner. One is dedicated to fine chemicals: Axyntis fine chemicals. Each division has its specificity even if they share the same safety and environment policy as well as common services to develop synergies.

The dyes division, Steiner, is a synthetic dye producer since 1881. Dyes are formulated for petroleum, oils, paper, cardboard, leather, textile, wood, ink, plus various other applications. 80 people are working for Steiner in France, St Marcel, and produce 8000 tons of formulated products per year. Steiner R&D Laboratory — 10 people — formulates and develops new technologies for the future of our customers. Steiner customers are located in Europe, America, Africa, and in the entire Mediterranean Basin. Concerned by environment protection, Steiner is equipped with a water treatment station. Steiner is certified ISO 9001 and ISO 14001.

Steiner has also a branch based in UK under the name of Steiner UK which operates for customers locally and brings an internal second source to secure the supply chain of its European customers.

The fine chemicals division, Axyntis fine chemicals, along with capacity of 380 m³ under cGMP, is split in four different plants, each of them having its own specificity:

These plants are complementary and enable a safety supply chain solution to the customers including internal back up strategy:

• Orgapharm is designed for key advanced intermediates and APIs for Pharmaceuticals industry and LCD under exclusive relationship;
• Centipharm is designed for exclusive key intermediates and generic API with its own regulatory support (US and European DMF and CEP);
• All’Chem is designed for key intermediates for electronic, agro and specialty;
• Synthexim is designed for key intermediates for pharma chemicals.

Both Orgapharm and Centipharm bring in addition Ramp;&D centers and Pilot capabilities which make these two plants a "one stop shop" for customers with a unique place for efficient transition phase between R&D and production (process development; scale up).

The four plants are Seveso II and two of them are high level compliant: this reflects the ability to perform complex chemistry and specific reactions that require high level of technical competence and specialized know-how.

With a competitive cost structure and a business network extended recently in the US and Asia, Axyntis group offers the best balance between expertise in specific reactions, flexibility, cost efficiency and time management for projects of innovative and fast growing companies in Europe, North America and Asia.

Orgapharm Rue du Moulin de la Canne 45300 Pithiviers France Tel.: +33 (0)2 38 06 20 00 Fax: +33 (0)2 38 30 24 24 Plant Director: Emmanuel Huet (emmanuel.huet@axyntis.com) A polyvalent plant with high level cGMP compliance in both intermediate and API productions.

Centipharm Chemin de la Madeleine BP 45249 06131 Grasse Cedex France Tel.: +33 (0)4 93 70 01 32 Fax: +33 (0)4 93 70 05 65 Works manager: Guy Duquesne (guy.duquesne@axyntis.com) Fine organic chemical products with both high added value and high level GMP compliance.

All'Chem Rue Marceau BP 577 03108 Montluçon France Tel.: +33 (0)4 70 03 75 25 Fax: +33 (0)4 70 03 08 79 Plant Director: Pascal Feniet (pascal.feniet@axyntis.com) For high production volumes and long-lasting production campaigns of chemical specialties.

Synthexim Rue des Mouettes ZI des Dunes 62100 Calais France Tel.: +33 (0)3 21 96 85 00 Fax: +33 (0)3 21 96 04 25 Plant Director: Bertrand Cazin (bertrand.cazin@axyntis.com) A 24/7 production plant operating in a five shifts system to supply your fine organic chemicals.

Steiner SAS 9, route de Rouen 27950 Saint-Marcel France Tel.: +33 (0)2 32 64 58 40 Fax: +33 (0)2 32 64 58 49 Plant Director: Laurent Choumery (laurent.choumery@axyntis.com) Our industrial mastering: a response to all your colouring needs.

Source: Axyntis